I-ozone sisibulali ntsholongwane esisebenzayo kwi-microorganism, umzekelo ibhaktheriya kunye nokungunda.Ibulala intsholongwane ngokutshabalalisa i-RNA kunye ne-DNA kunye nokubulala ibhaktheriya ngokutshabalalisa i-membrane yeseli.I-ozone iphinda isebenze ekususeni ivumba ngokubola kwekhemikhali yevumba elibi.Ngamafutshane, kwindawo yokuhlala yokucoca umoya, i-ozone ingafakwa kumagumbi, ezimotweni njl.njl.